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By preventing the clonal expansion of. Azathioprine is a thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group.
Your doctor will decide which strength you need.
Azathioprine chemical name. Azathioprine AZA sold under the brand name Imuran among others is an immunosuppressive medication. It is used in rheumatoid arthritis granulomatosis with polyangiitis Crohns disease ulcerative colitis and systemic lupus erythematosus and in kidney transplants to prevent rejection. It is taken by mouth or injected into a vein.
Common side effects include bone-marrow suppression and. Azathioprine is a thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohns didease and MS.
It has a role as an antineoplastic. Toxicity criteria on chemicals evaluated by OEHHA. OEHHA chemical database meta data Export database as CSV file If you are having trouble with the download and would like a copy of the database just drop me LaurieMonserratoehhacagov a note and I will provide you a csv file.
Azathioprine Prometheus Imuran is the main immunosuppressive cytotoxic substance. It is extensively used to control transplant rejection reactions. It is nonenzymatically cleaved to mercaptopurine that acts as a purine analogue and an inhibitor of DNA synthesis.
Mercaptopurine itself can also be administered directly. By preventing the clonal expansion of. LiverTox provides up-to-date unbiased and easily accessed information on the diagnosis cause frequency clinical patterns and management of liver injury attributable to prescription and nonprescription medications and selected herbal and dietary supplements.
The LiverTox site is meant as a resource for both physicians and patients as well as for clinical academicians and researchers who. The meaning of immunomodulator is a substance that affects the functioning of the immune system. The active ingredient in Toctino is alitretinoin a type of chemical that is naturally found in the body and is known as a retinoid as it is related to vitamin A.
Toctino comes as a capsule in two strengths 10 mg or 30 mg and is taken once a day with a meal. Your doctor will decide which strength you need. Toctino has been shown to be effective in patients with severe hand eczema.
The active substance in Remsima infliximab is a monoclonal antibody a type of protein that has been designed to recognise and attach to a specific structure called an antigen in the body. Infliximab has been designed to attach to a chemical messenger in the body called tumour necrosis factor-alpha TNF-alpha. This messenger is involved in causing inflammation and is found at high levels.