Acute exposure to toluene

Toluene is a clear colorless liquid with a distinctive smell. Benzene is an organic chemical compound with the molecular formula C 6 H 6The benzene molecule is composed of six carbon atoms joined in a planar ring with one hydrogen atom attached to each.

Aspiration hazard Category 1 H304 May be fatal if swallowed and enters airways.

Acute exposure to toluene. Access Acute Exposure Guideline Levels AEGLs Values On this page you will be able to access individual Acute Exposure Guideline Level AEGLs values that are intended to protect most individuals in the general population including those that might be particularly susceptible to the harmful effects of the chemicals. Find AEGL values in the table below using the chemical name or its CAS. TOLUENE Pictogram Signal word Danger Hazard statements H225 Highly flammable liquid and vapour.

H304 May be fatal if swallowed and enters airways. H315 Causes skin irritation. H336 May cause drowsiness or dizziness.

H361d Suspected of damaging the unborn child. H373 May cause damage to organs through prolonged or repeated exposure. Precautionary statements P201 Obtain special.

Toluene is a clear colorless liquid with a distinctive smell. Toluene occurs naturally in crude oil and in the tolu tree. It is also produced in the process of making gasoline and other fuels from crude oil and making coke from coalToluene is used in making paints paint thinners fingernail polish lacquers adhesives and rubber and in some printing and leather tanning processes.

Toluene C₆H₅CH₃ is a colorless liquid with a sweet pungent odor. Exposure to toluene can cause eye and nose irritation tiredness confusion euphoria dizziness headache dilated pupils tears anxiety muscle fatigue insomnia nerve damage inflammation of the skin and liver and kidney damage. Exposure Category 2 H373 May cause damage to organs central nervous system liver heart through prolonged or repeated exposure.

Aspiration hazard Category 1 H304 May be fatal if swallowed and enters airways. Hazardous to the aquatic environment. AEGLs Acute Exposure Guideline Levels Final AEGLs for Toluene 108-88-3 Exposure Period AEGL-1 AEGL-2 AEGL-3.

Lower Explosive Limit LEL 14000 ppm indicates value is 10-49 of LEL. Acute exposure to high levels of 24-toluene diisocyanate in humans via inhalation results in severe irritation of the skin and eyes and affects the respiratory gastrointestinal and central nervous systems CNS. Chronic inhalation exposure to 24-toluene diisocyanate in humans has resulted in significant decreases in lung function in workers an asthma-like reaction characterized by.

Acute exposure A single exposure to a toxic substance which may result in severe biological harm or death. Acute exposures are usually characterized as lasting no longer than a day. Chronic exposure Continuous exposure to a toxicant over an extended period of time often measured in months or years.

It can cause irreversible side effects. This section does not cite any sources. Benzene is an organic chemical compound with the molecular formula C 6 H 6The benzene molecule is composed of six carbon atoms joined in a planar ring with one hydrogen atom attached to each.

Because it contains only carbon and hydrogen atoms benzene is classed as a hydrocarbon. Benzene is a natural constituent of crude oil and is one of the elementary petrochemicals. A acute 8 8-hour C chronic.

Exposure averaging time for acute RELs is 1 hour. For 8-hour RELs the exposure averaging time is 8 hours which may be repeated. Chronic RELs are designed to address continuous exposures for up to a lifetime.

A medical monitoring program should be established for early detection and prevention of both the acute and chronic effects of exposure to TDI and TDA. Medical and work histories including previous exposure to TDI TDA or other toxic agents should be taken for each worker before job placement and updated periodically. The workers physician should be given information about the adverse.

Toluene Reagent Grade Created by Global Safety Management Inc. Toxicological information Acute Toxicity. 108-88-3 Toluene LD50 Rabbit.

108-88-3 Toluene LD50 Rat. The Case Studies in Environmental Medicine CSEM are self-instructional continuing-education primers designed to increase primary care providers knowledge of hazardous substances and aid in the evaluation of patients potentially exposed to hazardous substances. Exposure to Smoke from Fires.

The smoke released by any type of fire forest brush crop structure tires waste or wood burning is a mixture of particles and chemicals produced by incomplete burning of carbon-containing materials. All smoke contains carbon monoxide carbon dioxide and particulate matter PM or soot. Smoke can contain many different chemicals including aldehydes acid.

Route of Exposure. Direct skin contact can happen causing local skin irritation and rarely systemic disease. However prolonged exposure can lead to tissue breakdown and superficial partial thickness chemical burns.

Severe full-thickness chemical burns can lead to absorption and acute toxic systemic manifestations. Ingestion and inhalation. Volatile Organic Compounds VOCs are chemicals that evaporate easily at room temperature.

The term organic indicates that the compounds contain carbon. VOC exposures are often associated with an odor while other times there is no odor. Both can be harmful.

There are thousands of different VOCs produced and used in our daily lives. The exposure to health hazards can lead to diseases and illnesses that can manifest either immediately or after a long period of time after the exposure has stopped. Since these diseases are a consequence of exposure to hazards present in the work place they are known as occupational diseases.

Occupational hygiene uses methods for exposure identification and evaluation following the. Toxic leukoencephalopathy is an encephalopathy predominantly affecting white matter as a result of a toxic substance. The presentation can either be chronic or acute.

In the acute phase acute toxic leukoencephalopathy can have a characteristic and profound MR imaging appearance that is potentially reversible with therapy or removal of the offending agent. Emergency Medicine articles covering diagnosis lab studies imaging procedures prehospital care emergency department care prognosis follow-up. Peer reviewed and up-to-date recommendations written by leading experts.

Occupational exposure limits If a component is disclosed in section 3 but does not appear in the table below an occupational exposure limit is not available for the component. Agency Limit type Additional Comments 2-Methylpentane 107-83-5 ACGIH TWA500 ppmSTEL1000 ppm Toluene 108-88-3 ACGIH TWA20 ppm A4. There is a low potential for accumulation45 Xylene causes health effects from both acute 365 days exposure.

The type and severity of health effects depends on several factors including the amount of chemical you are exposed to and the length of time you are exposed for. Individuals also react differently to different levels of exposure. Measurements of a range of the common aircraft pollutants such as benzene toluene.

One example is a study examining the relationship between personal exposure to traffic emissions and acute respiratory health in school children with asthma residing in the Bronx New York which have the highest asthma incidence in New York City and state. Personal samples of PM 25 including the EC. Driven by legislation and evolving attitudes towards environmental issues establishing green solvents for extractions separations formulations and reaction chemistry has become an increasingly important area of research.

Several general purpose solvent selection guides have now been published with the aim to reduce use of the most hazardous solvents. This review serves the purpose. Excess exposure to fluoride can lead to a bone disease known as skeletal fluorosis.

Over many years this can result in pain and damage to bones.